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doi: 10.1002/oby.22594

When Long-Term Tirzepatide Makes Clinical Sense For people with a BMI over 30, metabolic syndrome, or type 2 diabetes, tirzepatide is increasingly being prescribed as a chronic maintenance medicationsimilar to blood pressure or cholesterol drugs

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They can advise you on restarting treatment at a lower dose to help prevent gastrointestinal side effects like nausea and vomiting that are common with Wegovy

Oral semaglutide should be considered as second-line therapy after metformin, particularly when weight is an issue and possibly in those at higher cardiovascular risk

But the two drugs differ in their mechanisms, making tirzepatide potentially more effective for some individuals
