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Individual variation in skin sensitivity, hydration status, and subcutaneous fat thickness means some patients experience more pronounced stinging than others at identical dose levels

Interpretation: Once-weekly semaglutide was superior to sitagliptin at improving glycaemic control and reducing bodyweight in participants with type 2 diabetes on metformin, thiazolidinediones, or both, and had a similar safety profile to that of other GLP-1 receptor agonists

This disease is currently devoid of strategies that change the natural course of this burdening illness

Strategically, this deal is Novo's most aggressive explicit commitment to the triple-agonist modality to date

Gastroenterology 137 , 865872 (2009)

It was also the most common reason for treatment discontinuation (Table 5)