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This delay contrasts with tirzepatide, which is currently accessible in the United States and has recently obtained approval in Europe.217 Adverse Reactions and Safety of GLP-1RAs and GLP-1/GIP Dual Receptor Agonist GLP-1RAs and dual agonists targeting GLP-1 and GIP receptors have demonstrated considerable efficacy in the treatment of T2DM and obesity

The result is harder, drier stool that becomes difficult to pass

The potential risks of pancreatitis and pancreatic cancer with GLP-1-based therapies are far outweighed by the proven and potential (cardiovascular) benefits

Drawing on OliveTree Partners' 360 analysis, here are concrete recommendations: 1

You can read the full article at Efficacy and safety of tirzepatide monotherapy compared with dulaglutide in Japanese patients with type 2 diabetes (SURPASS J-mono): a double-blind, multicentre, randomised, phase 3 trial In a phase 3 trial conducted in Japan, the efficacy and safety of tirzepatide, a new medication for type 2 diabetes, were compared to dulaglutide