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Conclusions Semaglutide 2.4 mg was cost-effective compared to D&E alone for patients with obesity (BMI30 kg/m2) and weight related comorbidities in Portugal, over a 40-year time horizon.

Some people use both as part of a broader protocol Lipo-C supporting efficient fat processing while semaglutide manages appetite

There are some studies implying that metformin might attenuate weight regain