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Compared with nonusers, adults taking GLP-1s had a: 17 percent lower risk of venous thromboembolism, or blood clots in the veins 31 percent lower risk of pulmonary embolism, a potentially life-threatening clot that travels to the lungs 21 percent lower risk of going to the emergency department 44 percent lower risk of all-cause mortality (death from any cause) Researchers also observed lower stroke rates among GLP-1 users, although this difference didnt reach statistical significance

According to KAM, between 4 percent and 7 percent of UK adults are currently using GLP-1 medications such as Ozempic, Wegovy and Mounjaro for weight loss

Pramlintide is an amylin analogue licensed for type 1 diabetes in the US but currently very few people are treated with it [4], and the risk of severe hypoglycaemia remains a barrier to its approval in the UK and Europe [5]

As the body of literature on this topic expands, more refined clinical guidance for the use of GLP-1RAs is expected to emerge

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Staying informed and maintaining open communication with your healthcare team can help you make choices that support your health and hemophilia management