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And if those conditions are met, can they move the needle on something actuarially relevant? While uncertainties remain, Bellomo said the emerging evidence increasingly points toward affirmative answers

Head-to-head trials (CONCLUDE and BRIGHT) showed comparable glucose control between the two, with some differences in hypoglycemia patterns depending on the trial design

If a patient on semaglutide starts experiencing more asthma symptoms, it may be necessary to increase the dose of their inhaled corticosteroid or add another medication to better control the inflammation

That visibility matters even more when the medication itself has built-in variability

Karan Desai along with CardioNerds Co-founders Dr