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GLP-1s in the Treatment of RA: What the Research Shows In theory, GLP-1s should improve RA symptoms
The FDA halted the sale of compounded GLP-1s, cutting off more affordable options for tens of thousands of patients
In a 48-week phase II clinical trial conducted on patients with type 2 diabetes and obesity, treatment with a dose of 10 mg/kg of bimagrumab resulted in a significant reduction in fat mass by 20.5% (compared to 0.5% in the placebo group), while lean body mass increased by 3.6% (as opposed to a decrease of 0.8% in the placebo group), leading to an overall body weight reduction of -6.5%, which was substantially better than the -0.8% observed in the placebo group
doi: 10.1152/ajpendo.2001.281.1.E155
Pycnogenol(R) and Centella asiatica to prevent asymptomatic atherosclerosis progression in clinical events
One promising optimization strategy involves the use of mRNA-encapsulated LNPs, such as Cas9 mRNA, instead of Cas9 plasmid DNA
