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Smoking and Nicotine Dependence NCT05530577: Effects of Semaglutide on Nicotine Intake and Smoking Lapse Status: Completed (Results not Reported) UNC trial investigating the effects of an approved GLP-1 receptor agonist on nicotine intake and reinstatement in humans

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However, a bulky aromatic group like the indole ring of Trp reduced potency, indicating that a steric factor should be also considered

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