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[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Lean MEJ, Leslie WS, Barnes AC, Brosnahan N, Thom G, McCombie L, et al

This drug is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist

At the 3.0 mg daily dose, liraglutide produced average weight losses on the order of ~8% in pivotal trials (SCALE program), with additional benefits in glycemic measures and cardiometabolic risk markers

Tirzepatide: Which Is the Best at Managing Weight Loss

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Additional Benefits Beyond weight and glycemic outcomes, studies have documented significant improvements in cardiovascular risk markers, liver fat reduction in NASH, improvements in obstructive sleep apnea, and enhanced quality of life metrics