glp-1 agonists for type 2 diabetes Comparing Ozempic, Wegovy and Other Drugs GLP-1RAs Reduce External Eating Behavior
Description
Glp-1 (Glucagon Like Peptide) Single molecule made in the small intestine and colon Causes the pancreas to make insulin when sugar is in the blood stream, in a dose dependent fashion (the more sugar you have, the more GLP-1 tells the pancreas to release insulin) Tells the gastrointestinal tract to slow down digestion Slows down carbohydrate absorption (so your blood sugar doesnt escalate quickly) Curbs appetite Animal studies show GLP-1 may promote regeneration of the beta cells in the pancreas by fighting programmed cell death (apoptosis)
In addition to aiding weight loss, semaglutide 2.4 mg also enhances eating regulation, lessens food cravings, and lessens the typical rise in appetite that follows substantial weight loss, all of which support continued weight control [112]
Furthermore, escalated relapse drinking after repeated withdrawal phases is attenuated by another GLP-1R agonist, AC3174 (Suchankova et al., 2015)
GLP-1 inhibits high-glucose-induced oxidative injury of vascular endothelial cells
Gene Ther
[DOI] [PMC free article] [PubMed] [Google Scholar] 17.Zaletel J., Barlovic D.P., Prezelj J
