how long have glp 1 been around agonists A timeline of GLP- 1 discovery and clinical development. Created in Everything we know about GLP-1s

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Potential long-term pancreatic risks: recurrent pancreatitis chronic pancreatic inflammation pancreatic exocrine insufficiency increased diabetes risk possible pancreatic fibrosis Though evidence is still evolving, ongoing inflammation could contribute to long-term pancreatic dysfunction

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Study results: what did they find

doi:10.1152/ajpendo.00642.2020 83

In some cases, salicylamine, a -KA scavenger, was added to the culture media and preincubated with the cells for 1 h at 37 C before further treatments