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Liraglutide (Saxenda) NICE Technology Appraisal TA664 recommends liraglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, within a specialist weight management service

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Metabolic and hormonal changes include restoration of baseline gastric emptying rates, return of pre-treatment appetite signals, and loss of the medication's insulinotropic effects

Mounjaro Dr Kovil summarised, Think of it this way: If you have diabetes, Ozempic or Mounjaro could be your go-to but if your focus is weight, heart, joints or liver health, Wegovy is the one designed for the bigger picture

Overview of Depression Major depressive disorder (MDD) is a highly prevalent mood disorder characterized by ruminative thoughts, impaired cognition and anhedonia, and attentional control deficits (Marchetti et al., 2012