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Dosing begins at a low level and is gradually increased as tolerated to maximize benefits and minimize side effects

Available online at: [Google Scholar] 26.Shim JS, Oh K, Kim HC

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Operational challenges arise due to the rapid enrolment of obesity trials given the high prevalence of obesity and associated unmet clinical need

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Understanding GLP-1 Tolerance and Weight Loss Plateaus Your body naturally develops tolerance to medications over time, including semaglutide and other GLP-1 receptor agonists
