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The All of Us Research programme supplied patient data for this analysis

Percent fat mass: Three studies (266 participants) were assessed for analyzing changes in percent fat mass and no significant reductions were observed with GLP-1 RAs/metformin (WMD: 1.07%

Looking at specific age groups, researchers found that nearly 19% of those 50 to 64 had tried a GLP-1 drug, compared to 13% of those 65 and older and 11% of those 30 to 49

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It is also worth noting that these effects of liraglutide in OVX animals occurred relatively quickly, with positive outcomes observed after just four weeks of treatment, consistent with in vitro data [57]