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Such effects appear to 'relate more to overall weight reduction and inactivity, not a direct toxic effect of the drugs,' says Dr Ajaz

Still, its far from a perfect, all-encompassing solution

Antihistamines like meclizine (Dramamine, Bonine) or dimenhydrinate can help with nausea, though they cause drowsiness
Large-scale CVOTs have demonstrated that GLP-1 RAs significantly reduce the incidence of MACE, including cardiovascular death, non-fatal MI and non-fatal stroke
