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In addition, there is substantial room for error in prescribing GLP-1s, and patients should be regularly monitored to ensure proper dosage, side effect management, and diet/exercise guidance

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11 In most studies that have reported significant adaptive thermogenesis, NREE accounts for most of the variance from predicted EE changes following weight loss

Understanding whether you carry variants associated with stronger appetite suppression, faster satiety, or metabolic efficiency can support a more informed conversation about dosing, timing, and realistic expectations