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[14] Jastreboff AM, et al

doi: 10.2147/CPAA.S276085 [DOI] [PMC free article] [PubMed] [Google Scholar] 19.Cork SC

Integrating a reduced-calorie diet, physical activity, and adequate protein intake ensures the medication's effectiveness in promoting muscle retention and significant weight reduction

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It found that GLP-1 use was associated with a significantly reduced long-term risk of TKA, and effects were greater with longer treatment duration and newer generation GLP-1s
