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doi:10.1016/j.neuropharm.2018.01.040 33
doi: 10.1056/NEJMoa2107519
Finally, restrain-free production run was carried out for each simulation, with a time step of 2 fs in the NPT ensemble at 310 K and 1 bar using the Nose-Hoover thermostat and the semi-isotropic Parrinello-Rahman barostat 32 , respectively
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