what is a glp 1 drug made from Weight loss with GLP-1 medicines does not result in disproportionate loss of muscle mass or function in obese mice and humans: Cell Reports Medicine Compounded GLP-1s: Why doctors worry
Description
Most patients notice changes in appetite and cravings within the first week
3.3 Mitochondrial dysfunction and oxidative stress Chronic hyperglycemia in patients with T2DM leads to peripheral insulin resistance, whereas impaired insulin signaling pathways in the brains of patients with AD lead to brain insulin resistance, both of which are closely related to mitochondrial dysfunction and OS (Zhang et al., 2023)
With the latest studies quantifying muscle loss at up to 40% of total weight reduction, its more important than ever for providers to proactively address this issue in practice
The most common adverse events are nausea and other gastrointestinal discomfort
Whats in development
Clinical data shows that patients typically regain 50-80% of lost weight within one year of stopping GLP-1 therapy without lifestyle maintenance
