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Never change your dose without consulting your healthcare provider first

Renal impairment pharmacists should check individual drug SPC for recommendations as dose adjustments may be required and can vary between individual drugs

For rheumatoid arthritis, the American College of Rheumatology recommends disease-modifying antirheumatic drugs (DMARDs) as first-line therapy, with methotrexate being the most commonly prescribed conventional synthetic DMARD

Vajdi, M., Safaei, E., Moeinolsadat, S., Mousavi, S., Seyedhosseini-Ghaheh, H., Abbasalizad-Farhangi, M., & Askari, G