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Description
Meanwhile, individuals who took a high-potency GLP-1 drug approved for obesity - such as semaglutide - had greater persistence at 14% three years after initiating therapy

At three, six, nine and 12 months following semaglutide initiation, women using hormone therapy experienced approximately 30% greater total body weight loss than the non-hormone therapy users

EVOLUTION OF GLP-1 THERAPY Despite the considerable momentum to acclaim GLP-1 as a preferred first-line injection therapy for the treatment of type 2 diabetes, other routes of administration than injections have long been pursued

While offering significant benefits, it may cause side effects like gastrointestinal issues, with serious risks including pancreatitis and potential thyroid cancer based on animal studies

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Nat Rev Endocrinol 17:48495
