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Without randomized, long-term studies on the use of GLP-1 RAs in a large sample size of HS patients with a wide range of ages, comorbidities, risk factors, and sexes and without any confounding factors, it is difficult to conclusively determine whether GLP-1 RAs are a definitive treatment for HS

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Preserving Lean Body Mass Ian Neeland, MD, FAHA, FACC, reviewed lifestyle and pharmacologic interventions to help preserve lean body mass in people receiving GLP-1-based therapies, which have been shown to produce significant weight loss

Studies have shown that dyshomeostasis of gut microbiota is associated with diseases such as inflammatory bowel disease (IBD), obesity, diabetes mellitus (DM), non-alcoholic fatty liver disease (NAFLD) and carcinomas [7,8,9,10]
