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CrossRef Large language model detects previously undiagnosed heart failure with preserved ejection fraction in patients with metabolic-associated fatty liver disease: A multicenter cohort study Xiaodan Lu, Xuliang Wang, Da Liu, Zhiyuan Zhang, Yuqiang Zhang, Tiancheng Zhang, Di Lu, Shengli Kuang, Chunjin Lai, Fushi Piao, Min Lin, Shengsong Zhu, Zhuchang Tian, Wei Fu, Yongbin Dai, Chengli Yao, Gang Li, Zhenzhong Zheng, Xiangbin Meng, Hongxing Luo, PLOS Digital Health.2026

A Distinct Profile of Tryptophan Metabolism Along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome

Adults with Type 2 diabetes who continued GLP-1 use for the entire 3-year period had a near 20% lower risk of major adverse cardiovascular events

Some patients may notice appetite, digestion, or eating-pattern changes earlier, while weight-related progress may take longer and depends on eligibility, dosing, lifestyle habits, and provider monitoring

This paper reports the discovery of a black mamba 3FTx that targets acid-sensing ion channels with potent analgesic activity

Peptidic exenatide and herbal catalpol mediate neuroprotection via the hippocampal GLP-1 receptor/beta-endorphin pathway