glp-1 agonist history GLP-1R Agonists for Weight Loss Discovery of GLP-1–Based Drugs for

There was not any great interest at that time. Even the Veteran Affairs Department, for whom Eng worked, wouldnt use department resources to file a patent for exendin-4

doi: 10.1001/jamainternmed.2022.0335 [DOI] [PubMed] [Google Scholar] 20

American College of Cardiology

Carmina, E., and R

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as highly effective therapies for weight reduction and glycemic control, and they show promise in improving fertility outcomes in women with obesity and PCOS [5,6]

That's a demanding bar, and it's the first time any head-to-head PsA trial has used it as a primary endpoint