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The middle lane in appetite control GLP-1 has become mainstream through drugs like Ozempic and Mounjaro that mimic a natural satiety signal and deliver striking weight loss

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Starting at the lowest dose (3mg) and escalating slowly is essential

Corkery, J.M

Because Glp1r mRNA is also expressed in the human OB 53 , it is intriguing to explore in future studies whether intranasal administration of GLP-1 agonists 54 could potentially exert their effects by acting in the OB (a site of persistent sensitivity to GLP-1 in obesity according to our data)

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