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In contrast, the effect on lean mass was minor and not significant relative to vehicle control (Supplemental Figure 1)
Some patients regain weight after stopping treatment, especially without a maintenance plan
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The key differentiator mechanistically is GCGR activation: tirzepatide has no glucagon component
In one such video, a svelte young woman on a couch asks a doctor, "I'm only looking to lose a couple of pounds, maybe use it temporarily." The doctor assures her it's fine for brief use
You also need to protect it from getting frozen so avoid putting your Wegovy pen in the coldest part of the fridge or next to the coolant fan
