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It's bloody expensive, and I think if it's not going to work, it's a waste of money." In her latest book, titled Being OldAnd Learning To Love It!, Dame Prue speaks about never putting on weight during her time on Channel 4's Great British Bake Off, and that she lived on a diet of cake and red wine

"So these conversations have been in my therapy room for several years now and they certainly do affect how treatment unfolds." The idea of using a weight loss drug could occur at a "pretty fragile time", she said, with potentially dangerous consequences

Symptoms include upper stomach pain, fever, yellowing of skin or eyes, and clay-colored stools

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[DOI] [PubMed] [Google Scholar] 39.Moretto TJ, Milton DR, Ridge TD, et al

Verdict at a Glance Pemvidutide and survodutide are both GLP-1/glucagon dual agonists being developed for obesity and MASH, but survodutide is further ahead in clinical development with more advanced Phase 3 programs, higher-tier regulatory designations (Breakthrough Therapy vs Fast Track), and greater weight loss in Phase 2 (18.7% vs 15.6%)
