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Among the various HFpEF phenotypes identified, the obesity-related phenotype characterized by visceral adiposity and insulin resistance appears to be the most prevalent (92)

Botfield HF, Uldall MS, Westgate CSJ, Mitchell JL, Hagen SM, Gonzalez AM et al (2017) A glucagon-like peptide-1 receptor agonist reduces intracranial pressure in a rat model of hydrocephalus

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The approach recommended by NICE and supported by UK clinical practice emphasises a structured, stepwise strategy rather than combining multiple weight loss medications

For years, obesity was explicitly excluded from Medicare drug coverage leaving millions of the highest-risk patients without access

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