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Moreover, GLP-1 has shown direct effects on diabetic CVD aspects including endothelial dysfunction, inflammation, angiogenesis, and cardiac remodeling

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2012 Jan;9(1):79

The only interaction of concern is pharmacokinetic: the delayed gastric emptying affecting oral hormone absorption

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The findings obtained from the SMART collaborative meta-analysis (SGLT2 Inhibitor Meta-Analysis Cardio-Renal Trialists), designed to evaluate the impact of SGLT2is on cardiovascular and renal outcomes based on the concomitant use or non-use of GLP1-RAs, included 12 controlled clinical trials with 73,238 participants, of whom 3065 (4.2%) received GLP1-RAs
