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Dempsey believes the drug binds to mast cell receptors and blocks the release of inflammatory mediators

Key Clinical Evidence Phase 2 Randomized Trial in Obesity (48 weeks) Jastreboff AM et al., New England Journal of Medicine, 2023 ClinicalTrials.gov: NCT04881760 The Phase 2 study evaluated multiple doses of retatrutide versus placebo over 48 weeks

(3) and for which a disease-causing sarcomere (or sarcomere-related) variant is identified or genetic etiology remains undetermined

Survodutide: GLP-1/glucagon dual receptor agonist

Side effects and safety considerations Semaglutide side effects are consistent regardless of the provider prescribing it