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Our understanding of the long-term safety of GLP-1 agonists remains limited, a concern that is particularly pertinent for chronic conditions such as pain and headaches
Managing B12 Levels While Using GLP-1/GIP Therapy Proactive management of vitamin B12 status should be integrated into the care pathway for patients prescribed GLP-1/GIP medicines , particularly those with additional risk factors for deficiency

Clinicians should continue reporting safety concerns and monitoring patient outcomes carefully
Diabetes 15 , 53 (2025)
