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And, above all, the genetic effects detected are small. What are the implications, and how does this fit with existing evidence

STARTER DOSE 3 mg STRENGTH 3 mg d NDC NUMBER 0169-4303-30 BOTTLE QUANTITY 30 x 3 mg per bottle THERAPEUTIC DOSE 7 mg STRENGTH 7 mg NDC NUMBER 0169-4307-30 BOTTLE QUANTITY 30 x 7 mg per bottle THERAPEUTIC DOSE 14 mg STRENGTH 14 mg NDC NUMBER 0169-4314-30 BOTTLE QUANTITY 30 x 14 mg per bottle d The 3 mg dose is intended for treatment initiation and is not effective for glycemic control

4, 5 Despite this success, about 50% of patients do not benefit from tamoxifen and frequent adverse drug reactions (ADR) including hot flashes, vasomotor and gynecologic symptoms as well as depression and diminished sexual functioning prevent particularly young women from staying on the drug