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On January 12, 2026, Chinas Center for Drug Evaluation (CDE) reached a major milestone by approving Shiling Pharmas Semaglutide Nasal Spray to enter clinical trials for long-term weight management

Semaglutide's single-receptor activation sometimes produces a gentler tolerability profile, allowing patients to pursue their weight loss goals with fewer digestive disruptions

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A thyroid ultrasound is not routinely required before starting tirzepatide unless your physician identifies a palpable thyroid abnormality or your medical history suggests specific risk factors

Let's dive into what the research actually shows