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While many people have found success from taking GLP-1s, this isnt the whole story

UN Environment Programme webpage, accessed Sep 2023.

When more water leaves the body than the amount that enters it, dehydration can result

Acts on Brain Appetite Centers: Crosses the blood-brain barrier to affect hypothalamic regions that control hunger and satiety, directly reducing appetite and food cravings

Summary The cloning of the glucagon gene, identification of GLP-1(7-37) as an intestinal hormone satisfying the criteria of an incretin and its development into a drug is a milestone in medicine

Large cardiovascular outcome trials (e.g., Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER), SUSTAIN) and post-marketing surveillance have not demonstrated an increased incidence of MTC in humans, though long-term pharmacovigilance continues given the rarity of this malignancy [30,62]