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Moreover, chronic treatment with liraglutide showed an increase in stem cell proliferation and differentiation into mature neurons in APP/PS1 mice and controls at all ages, which may have beneficial effects in neurodegenerative disorders like AD (168)

As well, exendin-4 (50 nM) and cyclic adenosine monophosphate (cAMP) response element-binding protein overexpression additively protected transplanted human islets in streptozotocin- (STZ-) induced diabetic nude mice [44]

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In addition, many obese individuals opt for dietary interventions and bariatric surgery

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The results showed that liraglutide had a modest positive effect on improving motor function and performed well in terms of safety and tolerability, although there were some manageable gastrointestinal side effects