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Severe gastrointestinal disease, particularly gastroparesis, may alter both efficacy and tolerability and requires careful consideration

Diabetes already puts you at an increased risk for NAION, and high blood pressure and sleep apnea are common complications in people who have overweight or obesity, Dr

Heart Failure Benefits The most significant recent advancement has been the demonstration of profound benefits in heart failure with preserved ejection fraction (HFpEF) across multiple pivotal trials, establishing GLP-1 RAs as transformative therapy for obesity-related heart failure (Table 7)

Specialist input should always be sought if there are any concerns with drug tolerability
