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Strengths Acts via multiple pathways (GLP-1, AMPK, microbiome) Has existing human data showing reductions in fasting glucose, HbA1c, lipids Support receptor expression and islet health Limitations Low absorption and bioavailability Gastrointestinal discomfort is common (diarrhea, cramping)

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Moxit Shah, DM EndocrinologyConsultant Endocrinologist | Ahmedabad Appointment: 9979992797 Introduction For years, people struggling with obesity were told to "eat less and exercise more." While healthy lifestyle changes remain the foundation of weight management, modern science has shown that obesity is a chronic hormonal disease, not simply a lack of willpower

In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively

This helps to increase insulin release after eating, lower glucagon levels, and slow down the emptying of the stomach, all of which contribute to improved blood sugar levels