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Based on Phase 2 trial data (published in the New England Journal of Medicine, 2023), subjects who discontinued retatrutide experienced gradual weight regain over several months consistent with the behavior observed with other GLP-1 class compounds

Ann NY Acad Sci 2003

Tissue Cell

These biological products contain peptide molecules that are susceptible to degradation when exposed to temperatures outside the recommended range

Most experience improvements over time with proper diet modifications

It belongs to a class of drugs known as GLP-1 receptor agonists, which mimic the action of the natural hormone glucagon-like peptide-1 (GLP-1) in the body