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As a result, maintaining weight loss with lifestyle modification alone can be challenging, due, in part, to metabolic adaptation as explained

Individual results will vary

Overall, results from the cardiovascular outcomes trials (CVOTs) completed for all marketed GLP-1 RAs in type 2 diabetes support a benefit in HF specifically in addition to the approved use in broad CVD risk reduction in people with type 2 diabetes (Sattar et al., 2021)

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Retatrutide is a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously

Common side effects, when they occur, are typically mild and gastrointestinal in nature, including bloating, flatulence, and temporary changes in bowel habits