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The scale-up of small-molecule manufacturing is also fundamentally more straightforward than peptide scale-up
Fourth Edition14 Montoya A, Bruins R, Katzman MA, Blier P
For severe obesity, every percentage point matters
The SURMOUNT trials demonstrated tirzepatide at 15 mg achieving 15% to 21% body weight loss by week 72, about 17 months
doi: 10.1371/journal.pone.0252353, 50
That is what SEMALEAN showed
