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The FDA does not review these medications for safety or efficacy

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But the definition was based only on the drugs mechanism of action, rather than any direct evidence of dopamines role in causing symptoms of ADHD, he says: The drug corrects the symptoms, so the assumption is that patients have a deficit of neurotransmitters. The efficacy of stimulant treatments led researchers to use brain imaging, genetics and experimental models of ADHD to probe dopamines role in the condition