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References Syn NL, Cummings DE, Wang LZ, Lin DJ, Zhao JJ, Loh M, Koh ZJ, Chew CA, Loo YE, Tai BC, Kim G, So JBY, Kaplan LM, Dixon JB, Shabbir A
l-Arginine, a potent insulin secretagogue [309], also stimulates GLP-1 release from isolated rat intestine, and, when given orally, augments GLP-1 and insulin levels and improves glucose tolerance in mice, effects that are absent in GLP-1R KO mice [305]
However, this should always be discussed with a doctor before making changes
The extra pathway is the main reason researchers expect strong metabolic effects from retatrutide
Author contributions NK and NS conceived the idea and conceptualized the study
