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The Maintenance Phase Reality After reaching your plateau weight, treatment transitions from active loss to maintenance

The paradigm shift that began with EMPA-REG OUTCOME and LEADER has led to SGLT2 inhibitors and GLP-1 RA being recognised not only in international diabetes guidelines, but also as an important consideration for patients with T2D in CVD prevention [28,29,30, 76, 77], HF [133,134,135] and CKD [41, 102] guidelines, where it has been suggested that these agents should be considered early in the course of diabetes management

Upregulated INHBA expression is associated with poor survival in gastric cancer

Ive written about health costs here earlier this year (See here), and medications represent a substantial segment of those costs

In T2D mice, oral administration of Lactobacillus casei increased the abundance of Bacteroidetes, Bifidobacterium , and Lactob acillus, and butyrate production increased, which stimulated GLP-1 secretion (53)
