once a week glp-1 agonist Current Insights, Advantages and Challenges of Small Molecule Glucagon-like Peptide 1 Receptor Agonists: Scoping Review GLP-1 Medications for Weight Loss:

Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M) Diabetes Care

[PubMed] [Google Scholar] 26.Gupta K., Raja A

If you have type 2 diabetes, GLP-1 medications address both weight and blood sugar, making them the clearly superior option

For more than 50 years metformin has been used to control hyperglycaemia in patients with type 2 diabetes, and it is currently recommended as the first-line drug treatment along with lifestyle modification [1]

Compared with db/db mice, the Low and High groups treated with berberine had lower blood glucose levels after intraperitoneal injection of glucose and insulin (Figures 1E, G)

And the same may be true to GLP-1 agonists: the proof of their repurposed uses their true pros and cons may only be observed in many years' time