how do the glp 1 drugs work Health Feed how does a glp 1

doi: 10.1055/a-2266-1503

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These agents include semaglutide (Ozempic for diabetes, Wegovy for obesity), liraglutide (Victoza for diabetes, Saxenda for obesity), dulaglutide (Trulicity, diabetes only), and tirzepatide (Mounjaro for diabetes, Zepbound for obesity)with tirzepatide being a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist

Whether the renal arterial GLP-1R mediates the antiinflammatory actions of GLP-1 medicines in the kidney remains to be determined

[1] [2] The physiologic role of GLP-1 includes stimulating glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and promoting satiety through central nervous system pathways

Readouts from the first clinical trials with triagonists will determine if such triple agonism has the curative potential that the preclinical data suggest