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The second strategy focuses on DPP-4 inhibitors, which prevent the rapid degradation of endogenous GLP-1 by inhibiting the DPP-4 enzyme, thereby extending the hormone's activity

49 GLP-1RA is primarily used for the treatment of T2DM 68 and works by mimicking the action of the naturally occurring hormone GLP-1, which is released by the intestines in response to food intake

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Studies have used doses ranging from 100 million to 10 billion CFU daily, with beneficial effects observed across this range

Recognizing this, there is a huge range of variability in analyst forecasts of the GLP-1RA market opportunity, its impact on consumption and industry implications