does metformin increase glp 1 Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells Gastrointestinal Mechanisms Underlying the Cardiovascular

Diabetes leads to a significantly accelerated incidence of various related macrovascular complications, including peripheral vascular disease and cardiovascular disease (the most common cause of mortality in diabetes), as well as microvascular complications such as kidney disease and retinopathy

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Heart failure patients could be the next group to benefit from GLP-1 agonists, which are currently approved for the treatment of diabetes and obesity.

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