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To assess the associations of semaglutide with recurrent CUD, the study population included 2034 patients who had active medical encounters for the diagnosis of obesity in 6/202112/2022, were for the first time (new users design) prescribed semaglutide or non-GLP-1RA anti-obesity medications during 6/202112/2022 (time zero or index event), had a diagnosis of CUD on or before the index event, and had a diagnosis of at least one of obesity-associated comorbidities on or before the index event

Protein concentrations were measured via a BCA assay (Perkin Elmer), and the respiration rates were normalized to the protein concentration

Table 2D A review of preclinical studies of GLP-1 and GLP-1RAs in stroke

In MS, peripherally activated T cells cross the blood-brain barrier (BBB) into the CNS, where they are re-activated and secrete cytokines to exert their effector functions [196]
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Targeting epicardial adipose tissue: a potential therapeutic strategy for heart failure with preserved ejection fraction with type 2 diabetes mellitus