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When saliva flow drops, all of that protection is reduced

Limited long-term human data prevents definitive safety conclusions, but decades of research suggest low risk with proper use

A 2024 study in Translational Psychiatry used positron emission tomography (PET) imaging to measure dopamine transporter binding in the striatum of adults with obesity before and after 12 weeks of semaglutide treatment

Such a low purity is concerning, Mackey says, because you have no idea what the rest is and whether it could be harmful when injected. And though the semaglutide peptide sellers included research use only on their labels, one seller offered injection guidance, and others touted the potential health and weight-loss benefits of their products