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Normally, myocardial energy metabolism relies mainly on fatty acids (70%), with glucose, ketone bodies, and lactate as supplementary sources

Nearly all of KMT2A rearrangements are classified as translocation mutations, which produce a fusion protein that binds to the menin protein, triggering the development of leukemia

Cell Physiol Biochem 36 : 23662378

Metabolic effects of cigarette smoking

Revenues continued to fall 19.5% YoY to $14.88 billion, still beating the consensus estimates of $13.87 billion

There is also a pipeline of novel drug candidates, such as small-molecule, once-a-month injectable, and dual-triple GLP-1 agonists with the GIP and glucagon receptors